Postdoctoral Research Associate (gn*)

(*gn=gender neutral)

The research group "cryoEM of complex nanosystems" at the Center for Soft Nanoscience /University is offering a job position, initially limited for 2 years.

Full-time with 100%
Remuneration according to TV-L E13

The overall aim of the project is to improve our understanding of the architecture of the yeast peroxisome using cryoEM single particle analysis/cryo-electron tomography and advanced image processing workflows. We aim to elucidate the in situ structures of macromolecular complexes that play a critical role in peroxisomal biogenesis and peroxisomal disorders.
The line of research will be carried out using the new state-of-the-art cryo-EM infrastructure recently established at the Centre for Soft Nanoscience, including:

• a Titan KRIOS G4 microscope with Falcon 4i detector and SelectrisX energy filter
• an Aquilos II cryoFIBSEM with iFLM and lift-out
• a Talos 120C screening cryoEM
• access to state of the art GPU clusters and cloud storage

Your tasks:

• CryoEM sample preparation
• Optimise workflows for cryo-correlative light and electron microscopy (cryoCLEM)
• Preparation of thin cryo lamellae for cryoET (cryoFIB milling)
• CryoET/image processing/sub-tomogram averaging
• CryoEM single particle analysis
• Molecular modelling

Our expectations:

• Applicants must have a PhD in Biology, Chemistry, Physics or a similar scientific field
• Experience in cryoEM/structural biology
• Experience in structure elucidation by cryo-electron tomography and in the use of the corresponding software packages would be an advantage
• Good IT skills; experience with Python is an advantage
• A good command of written and spoken English
• Furthermore, soft skills such as the ability to work in a team, communication skills, organisational skills and independent working methods are required

We offer:

• Our team, led by Prof Gatsogiannis, consists of over 12 researchers, postdocs, engineers and PhD students of different nationalities, forming a friendly and dynamic group.
• Your new workplace is located in a world-class interdisciplinary research centre in Münster. with state-of-the-art cryoEM equipment and a modern protein biochemistry and cell biology laboratory.
• Targeted, individual training and development opportunities
• A highly collaborative research environment

If you have any questions in advance, please contact Prof. Dr. Christos Gatsogiannis, T 0251 83 34411.

Please submit your candidacy by 13.12.2023 via our online application form!

The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.