PhD Student (gn*) Biology, Biochemistry, Biomedicine, Experimental Medicine, Medicine

Fixed-term of three years | Part-time with 65% (25 hours/week) | Salary according to TV-L E13 | Department of Anesthesiology, Intensive Care and Pain Therapy

We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.

To meet our high standards every day, we are looking forward to your scientific expertise in the Department of Anesthesiology, Intensive Care and Pain Therapy – ideally with you on board!

The Jorch Lab studies the mechanisms of immune cell activation and recruitment in various in vitro and in vivo models of inflammation and infections. In detail, this project addresses the functional analysis of PSTPIP1, a protein that is relevant in certain autoinflammatory diseases, and the alarmins S100A8/A9 in inflammasome activation using mainly biochemical and cell biological methods.

This project provides an exciting and dynamic research environment with a broad range of state-of-the-art technologies from various departments, with excellent opportunities for networking and collaborations.

RESPONSIBILITIES:

• Culture of immortalized cell lines
• Generation of mutant cell lines via CRISPR/Cas9
• In vitro interaction studies with recombinant proteins and in vivo interaction studies using immortalized cell lines
• Functional assays including inflammasome activation, cytokine release, ROS production, Phagocytosis, adhesion and migration

REQUIREMENTS:

• Above average Master's degree in biology, biochemistry, biomedicine, experimental medicine, medicine or other related subjects / life sciences
• Strong knowledge in molecular biology, biochemical and immunological techniques such as western blot, flow cytometry, cell culture, ELISA
• Experience in working with mice or imaging techniques is not essential, but would be beneficial
• Independent, reliable and structured way of working with a good sense of quality is essential
• High motivation, flexibility, good self-organization and team working abilities
• Ability to analyse and critically reflect scientific data
• Determination, creativity, profound knowledge and resilience to successfully complete the project and advance the scientific field
• Very good written and spoken English language skills
• Enthusiasm and passion for doing and understanding science
• Ability to organize and prioritize work

WE OFFER:

• Training, further development and working with state-of-the-art technologies in Inflammation Research
• Participation and contribution to scientific group meetings, network meetings and conferences
• Encouragement and support for the preparation of research papers and scientific networking
• Excellent options for networking and collaboration through collaborative research networks
• An exciting and dynamic research environment
• Support for personal development and training

Apply now via our career portal until 07.05.2025.

Formal Applications Should Include:

• A cover letter with a brief statement of research experience, research interests, research techniques and career goals
• A CV with education certificates and grades
• Contact information of two possible referees (address, phone number and email)